research August 13, 2026 via J Clin Med

Preoperative Surgical-Field Antisepsis with a pH-Optimized Sodium Hypochlorite Wound Cleanser in Microsurgical Diabetic Foot Reconstruction: A Single-Center Feasibility Study.

Diabetic foot ulcers are a serious complication of diabetes that can lead to infection and amputation if not treated properly. This study explored a new method of preparing the foot before surgery to reduce infection risk and improve healing. Researchers tested a wound cleanser containing sodium hypochlorite (a type of bleach) but with a balanced pH to be gentle on tissues. In a small group of 20 patients with diabetic foot ulcers undergoing microsurgery, the cleanser was used before surgery. Results showed that the cleanser was safe and effective in reducing bacteria on the skin without harming tissues. Notably, none of the 20 patients developed a surgical site infection, suggesting the cleanser may be beneficial. However, this was a small, non-randomized feasibility study, so larger trials are needed to confirm these findings. This research is significant because it could lead to a simple, inexpensive way to improve outcomes in diabetic foot surgery, potentially reducing the risk of amputation and enhancing recovery.

Medically reviewed by Professor Wang Cheng, MD

Key takeaways

  • A pH-optimized sodium hypochlorite cleanser was used before diabetic foot surgery to disinfect the skin.
  • In a study of 20 patients, none developed a surgical site infection after using the cleanser.
  • The cleanser was safe and did not harm the wound or surrounding tissues in these patients.
  • This approach could be a cost-effective way to reduce infection risk, but larger studies are needed.
  • Ask your doctor if this type of antiseptic cleanser is right for your diabetic foot ulcer surgery.
  • If considering surgery for a diabetic foot ulcer, discuss infection prevention methods with your healthcare team.

Editor's note

Imagine your foot is like a garden that needs to be cleared of weeds before planting new seeds. This cleanser acts like a gentle but powerful weed killer that cleans the area without damaging the soil. For you, who may have been told that amputation is the only option, this research offers a glimmer of hope: a simple step during surgery could lower the risk of infection, which is a major cause of failure in limb-saving procedures. While this specific cleanser is not yet a standard part of all diabetic foot surgeries in China, it is being explored at specialist centers, and your surgeon may be able to tell you more about the infection prevention protocols they use. So, when you discuss surgery with your doctor, don't hesitate to ask about what they do to reduce infection risk—it could make a difference in your recovery.

This content summarizes published medical research for educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making treatment decisions.

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